
scRNA-seq
Gemcitabine efficacy across tumor types: A pan-cancer study of 50 cancer cell lines
Gemcitabine (2′,2′-difluorodeoxycytidine) is a nucleoside analog widely used in the treatment of various solid tumors, including pancreatic, non-small cell lung, breast, and bladder cancers. Although its primary mechanism involves inhibition of DNA synthesis leading to S-phase arrest and apoptosis, variability in drug response across different cancer types remains